A paper as a result of a collaboration between the REdesign Lab and the Biotherapeutics Lab (PI: Dr. Ke Cheng) was published as the cover story in this week’s issue of Science Translational Medicine. Acellular cardiac patches were made from porcine heart extracellular matrix and synthetic cardiac stromal cells. These off-the-shelf patches were able to improve repair after myocardial infarction in rats and pigs.
NC State University featured this study in a recent news article.
Additionally, the study was featured in Nature Reviews Cardiology as a Research Highlight!
Citation is below:
Huang K, Ozpinar EW, Tang J, Shen D, Su T, Qiao L, Liang H, Mathews K, Scharf V, Freytes DO and Cheng K. An Off-the-Shelf Artificial Cardiac Patch Improves Cardiac Repair After Myocardial Infarction in Rats and Pigs. Sci. Transl. Med. 12, eaat9683 (2020).
