REdesign Lab

Dr. Donald O. Freytes, Ph.D.; Joint Department of Biomedical Engineering at UNC-CH and NCSU

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Dr. Mora-Navarro Receives 2020 BME Department Achievement Award

The UNC/NCSU Joint Department of BME has announced their 2020 Department Achievement Awards and we are proud to announce that REdesign postdoctoral research associate Dr. Camilo Mora-Navarro has received the Postdoctoral Fellows Award for Outstanding Research Achievement!

The department had this to say about Dr. Mora-Navarro:

“Dr. Mora-Navarro (Freytes Lab) has pushed the field of manufacturing extracellular matrix scaffolds for regenerative medicine to the next level, published 4 refereed papers in 2020, filed a patent application, and excelled at training undergraduate researchers–one of whom has achieved co-authorship on a publication.”

Dr. Mora-Navarro was nominated for this award and selected by a panel of professors from both NC State and UNC. The awards were announced via email and on the BME website. He will receive a commemorative plaque along with this recognition.

We couldn’t agree more with the decision! Congrats, Dr. Mora-Navarro!

New Paper Accepted at Biomedical Materials

Starting off 2021 with good news, the REdesign lab would like to announce a new study published in Biomedical Materials! Led by REdesign Lab postdoctoral researcher Camilo Mora-Navarro, PhD, this newly-accepted publication takes a detailed look at the transcriptomic response of human peripheral blood-derived macrophages when seeded on commonly used surgical meshes, particularly of a novel poly-4-hydroxybutyrate (P4HB) mesh. Results of this study provide valuable information of the potential immune response when these meshes are implanted in vivo or clinically. This study was generously funded by TEPHA, Inc. and is a shining example of collaborative work between academia and industry.  

The citation is below: 

Mora-Navarro C, Ozpinar EW, Sze D, Martin DP, and Freytes DO. Transcriptome-Targeted Analysis of Human Peripheral Blood-Derived Macrophages When Cultured on Biomaterial Meshes. Biomedical MaterialsPublished Ahead of Print (January 2021). 

What a great start to the new year!

Emily Selected as 2021 Horizon Award Recipient from UNC-CH Graduate School

A big congratulations goes to REdesign PhD candidate Emily W. Ozpinar, who was recently selected as a 2021 Horizon Award recipient by The Graduate School at University of North Carolina-Chapel Hill (UNC-CH)! The Horizon Award, as well as the Impact Award, are annual awards given to outstanding graduate students whose research has benefited, or is likely to benefit North Carolina and its citizens. Each department at UNC-CH may nominate up to two graduate students, who then go through a rigorous application process. In early January, Emily, along with a description of her research, will be featured on The Graduate School’s website and will be further recognized  at the Annual Graduate Student Recognition Celebration.

You may read more about this fantastic news on The Graduate School’s website. It is also posted on the UNC-CH homepage, on the BME department website and Emily is specially featured in a post from UNC Healthcare as a graduate student in the School of Medicine and UNC/NCSU Joint Department of Biomedical Engineering.

Bravo, Emily!

Two REdesign Undergraduates Selected for 2020-21 Abrams Scholar Program

Congratulations to REdesign undergraduate research assistants Caroline Dau and Bhairavy Puviindran, who have been recently selected for the 2020-21 Cohort of Abrams Scholars! The Abrams Scholars program, sponsored by the NCSU College of Engineering and the UNC/NCSU Joint Department of Biomedical Engineering, provides funding for outstanding BME undergraduate researchers to work on projects proposed by faculty members. Scholars are selected from a competitive pool of applicants and are expected to present their findings at the end of the Spring semester. You may read more about the funded projects and students in the announcement from the BME website.

Way to go, Caroline and Bhairavy! We look forward to a productive year of research!

Andreea and Emily Present at 2020 NCSU’s Biomaterials Day

On Friday, October 30th, the NC State University Society for Biomaterials student chapter virtually hosted their annual 2020 Biomaterials Day,  featuring three event speakers and six student talks. This year, REdesign Lab PhD candidates Andreea (Badileanu) Biehl and Emily W. Ozpinar were selected as student speakers and were able to present data from their latest publications. Their talks were as follows:

“New Automated Tool for the Derivation of Extracellular Matrix Biomaterials from Porcine Soft Tissues” by Andreea (Badileanu) Biehl

“Porcine-Derived Extracellular Matrix Hydrogels as Three-Dimensional Platforms for Mast Cell Culture and Maturation” by Emily W. Ozpinar

It was a great event!

New Review Paper Accepted at Tissue Engineering, Part B

We are proud to announce a recent paper acceptance at Tissue Engineering Part B! The review, led by PhD Candidate Emily W. Ozpinar, was a collaboration between Dr. Glenn Cruse of the College of Veterinary Medicine and include recently graduated REdesign undergraduate research assistant  Ariana L. Frey as an author. We invite you to read this review on mast cell-biomaterial interactions!

Ozpinar EW, Frey AL, Cruse G and Freytes DO. Mast Cell-Biomaterial Interactions in Tissue Repair. Tissue Engineering Part B. Published Online (November 2020). https://doi.org/10.1089/ten.TEB.2020.0275.

Great work!

New Paper Accepted at Tissue Engineering, Part A

The members of the REdesign Lab are delighted to inform you of a new study, led by PhD candidate Emily W. Ozpinar and former undergraduate research assistant Ariana L. Frey, accepted at Tissue Engineering, Part A! Through a collaboration with the NCSU College of Veterinary Medicine,  our study explores the use of porcine-derived dermis extracellular matrix hydrogels as a substrate for mast cell viability and maturation. The project has been generously funded by the Comparative Medicine Institute’s Young Scholar Program (YSP) and Summer Interdisciplinary Research Initiative (SIRI), the UNC-CH/NCSU Joint Department of Biomedical Engineering’s Abrams Scholar Program and the NCSU Office of Undergraduate Research. We thank these funders for their support.

The citation is below:

Ozpinar EW*, Frey AL*, Arthur GK, Mora-Navarro C, Biehl A, Snider DB, Cruse G and Freytes DO. Dermal Extracellular Matrix-Derived Hydrogels as an In Vitro Substrate to Study Mast Cell Maturation. Tissue Engineering Part A. Published Online (October 2020).

*= Co-first authors

Congratulations to all the authors!

Andreea and Emily Awarded 2020 CMI FTE Scholarships

Congratulations to REdesign PhD candidates Andreea Badileanu and Emily W. Ozpinar for being awarded 2020 Associate Member Scholarships from the Functional Tissue Engineering (FTE) group of the Comparative Medicine Institute! These scholarships of $500 will support research and professional development in the upcoming academic year for Andreea and Emily. This funding was open to all graduate student and postdoctoral associate members of the CMI FTE group through an application process.

We thank the CMI FTE group for this funding.

Way to go, Andreea and Emily!

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