Title: Research Associate,
UNC-CH/NCSU Joint Department of Biomedical Engineering
My research focuses on harvesting the therapeutic potential of Extracellular Matrix (ECM) based biomaterials while uncovering their complexity and pursuing industrial technology translation. Injuries in the vocal folds and heart are part of a large group of challenging lesions affecting the right functioning of tissue and organs, impacting the lives of millions of people across the US and worldwide. Arguably, the current treatments do not fully satisfy tissue regeneration for a full recovery, and the treatment options may be limited. Our group works in the development of ECM-scaffolds for wound healing application in the vocal fold tissue, heart, and tendon. A significant challenge for a full recovery of these tissues after an insult lies in their complex protein composition required for their right functioning. ECM-scaffolds are complex biomaterials derived from the decellularization process from different tissues or organs, with tremendous potential in the biomedical research field and clinically translatable to humans. We have developed novel technologies (bioreactors) to decellularize ECM-scaffolds from porcine vocal folds and heart tissue. The appropriate decellularization platform approached enables us to derive biomaterials with a biomolecular-specific composition intrinsically related to the organ/tissue source. Also, we have produced injectable forms from the decellularized ECM to less invasively harvest the therapeutic potential of the biomaterials. Our vision is to use the developed scaffold by themselves or by incorporating exogenous components that enhance regenerative outcomes.
Ph.D. Chemical Engineering – University of Puerto Rico-Mayaguez
Postdoctoral training, University of Texas – M.D. Anderson Cancer Center, Houston, TX
Camilo Mora-Navarro is a goal-oriented scientist and Chemical Engineer with 9+ years’ experience in being part of multidisciplinary research teams in academia and in industry. Camilo has worked on the expression, purification, and characterization of proteins. He has also worked on the development of biomaterials with a focus on wound healing applications, antimicrobial development therapies, and stem cell therapy components. Moreover, he has been involved in gene editing projects and manufacturing/quality in the plastic industry at an early stage of my career.
Camilo has mentored more than 20 undergraduate students from different disciplines and backgrounds. He enjoys being involved in educational outreach projects, volunteering activities, as well as mentoring others.
My current interest topics are:
cell therapies and nanovesicles,
protein expression and purification,