Dr. Donald O. Freytes, Ph.D.; Joint Department of Biomedical Engineering at UNC-CH and NCSU

Month: June 2020

Paper accepted! “Fast Automated Approach for the Derivation of Acellular Extracellular Matrix (ECM) Scaffolds from Porcine Soft Tissues”

The REdesign Lab is very excited to announce that our most recent publication was accepted in the journal ACS Biomaterials Science & Engineering!

In this work, our lab members developed a new industry scalable tool to derive ECM scaffolds for hydrogel production from porcine heart and vocal fold tissues. The paper is in press and will soon be available online!

The main authors, Dr. Camilo Mora-Navarro and Andreea Badileanu have also worked with the Office of Research Commercialization at NC State to file a Provisional Patent Application (No. 63/024,870) for their invention titled: “Fast Automated Approach for the Derivation of Acellular Extracellular Matrix Scaffolds from Tissues.”

The process just started, but we are very excited about the newly developed system, which will propel  the automated production of ECM hydrogels forward.

Special thanks goes to Jenkins, Wilson, Taylor & Hunt, P.A., the REdesign lab members, and our funding sources: National Institutes of Health/National Institute on Deafness and Other Communication Disorders (R01DC017139, R01DC017743).

REdesign Lab 2019-2020 Abrams Scholars Finish and Present Their Research

Congratulations to the four Abrams Scholars from the REdesign Lab, who have completed their year of sponsored independent research. The Abrams Scholarship program in the UNC-CH/NCSU Joint Department of Biomedical Engineering (BME) provides stipends to top BME undergraduate student researchers to conduct independent research in BME and BME-affiliated labs. Their research culminates in May when the scholars deliver presentations to the BME department on their progress and findings. The 2019-2020 Abrams Scholars from the REdesign Lab and their presentation titles are as follows:

Amber DetwilerComparing Dermal Fibroblast Donor Age and Time in Culture for In Vitro Hydrogel-Based Skin Graft Modeling

Ariana FreyEngineering a Three-Dimensional In Vitro Platform for Mast Cell Maturation

Cody Helm – Engineering a Nanocarrier Drug Delivery Model to Target Mast Cells in an Extracellular Matrix Hydrogel

Isabel MayoMicrofabrication of a Heart-on-a-Chip Platform for High-Throughput Screening

We thank the Abrams Scholar program and the UNC-CH/NCSU Joint Department of Biomedical Engineering  for funding these great students throughout the 2019-2020 school year. Great work!

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