Dr. Donald O. Freytes, Ph.D.; Joint Department of Biomedical Engineering at UNC-CH and NCSU

Month: April 2020

REdesign Undergrads Present at Spring 2020 NCSU Undergrad Research Symposium

Three REdesign Lab undergraduate researchers presented their work at the North Carolina State University (NCSU)’s 29th Annual Spring Undergraduate Research & Creativity Symposium! This spring, the symposium took place online, where undergraduate researchers across the University showcased their projects through a poster/video format.

The following REdesign Lab researchers presented:

Amber DetwilerComparing Dermal Fibroblast Donor Age and Time in Culture for In Vitro Hydrogel-Based Skin Graft Modeling

Ariana FreyEngineering a Three-Dimensional In Vitro Platform for Mast Cell Maturation

Cody Helm – Engineering a Nanocarrier Drug Delivery Model to Target Mast Cells in an Extracellular Matrix Hydrogel

Amber, Ariana and Cody are also Abrams Scholars through the BME department, previous Summer Interdisciplinary Research Initiative (SIRI) students through the Comparative Medicine Institute (CMI), and recipients of NCSU Office of Undergraduate Research (OUR) grants. We thank these generous programs for their funding.

Congratulations to another completed school year of productive research!

Collaboration with Cheng Lab Published in Science Translational Medicine

A paper as a result of a collaboration between the REdesign Lab and the Biotherapeutics Lab (PI: Dr. Ke Cheng) was published as the cover story in this week’s issue of Science Translational Medicine. Acellular cardiac patches were made from porcine heart extracellular matrix and synthetic cardiac stromal cells. These off-the-shelf patches were able to improve repair after myocardial infarction in rats and pigs.

NC State University featured this study in a recent news article.

Additionally, the study was featured in Nature Reviews Cardiology as a Research Highlight!

Citation is below:

Huang K, Ozpinar EW, Tang J, Shen D, Su T, Qiao L, Liang H, Mathews K, Scharf V, Freytes DO and Cheng K. An Off-the-Shelf Artificial Cardiac Patch Improves Cardiac Repair After Myocardial Infarction in Rats and Pigs. Sci. Transl. Med. 12, eaat9683 (2020).

Andreea Becomes Ph.D. Candidate

A big congratulations goes to  graduate student Andreea Badileanu, who passed her oral preliminary exam, becoming REdesign Lab’s newest PhD candidate! We all look forward to the great and innovative work she will conduct during her candidacy.

Way to go, Andreea!

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